The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
Oct. 14, 2021
Applicant:
Aurigene Oncology Limited, Bangalore, IN;
Inventors:
Kavitha Nellore, Bangalore, IN;
Subramanya Hosahalli, Bangalore, IN;
Assignee:
Aurigene Oncology Limited, Bangalore, IN;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4192 (2005.12); A61K 31/454 (2005.12); A61K 31/496 (2005.12); A61K 31/5377 (2005.12); A61P 35/02 (2005.12);
U.S. Cl.
CPC ...
A61K 31/4192 (2012.12); A61K 31/454 (2012.12); A61K 31/496 (2012.12); A61K 31/5377 (2012.12); A61P 35/02 (2017.12);
Abstract
The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. Compounds of formula (I) have substituents R, Rand Rwhich have the meanings given in the specification, and pharmaceutically acceptable salts thereof.