The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Sep. 21, 2020
Applicant:

Gen-probe Incorporated, San Diego, CA (US);

Inventors:

David Buse, San Diego, CA (US);

David Howard Combs, San Diego, CA (US);

Norbert D. Hagen, Carlsbad, CA (US);

David Opalsky, San Diego, CA (US);

Bruce Richardson, Los Gatos, CA (US);

Anita Prasad, Los Gatos, CA (US);

Keith Moravick, Los Gatos, CA (US);

Tyler Moore, Los Gatos, CA (US);

Byron J. Knight, San Diego, CA (US);

Assignee:

GEN-PROBE INCORPORATED, San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2017.12); B01L 7/00 (2005.12); G01N 21/64 (2005.12); B01L 9/06 (2005.12);
U.S. Cl.
CPC ...
C12Q 1/686 (2012.12); B01L 7/52 (2012.12); G01N 21/6452 (2012.12); B01L 9/06 (2012.12); B01L 2200/141 (2012.12); B01L 2200/142 (2012.12); B01L 2300/042 (2012.12); B01L 2300/0654 (2012.12); B01L 2300/0829 (2012.12); B01L 2300/0851 (2012.12); B01L 2300/1822 (2012.12); G01N 2021/6482 (2012.12); G01N 2021/6484 (2012.12);
Abstract

An apparatus for performing nucleic acid amplification reactions includes a thermally-conductive receptacle holder that includes multiple receptacle wells. Each well can receive a receptacle and has a through-hole extending from an inner surface of the well to an outer surface of the holder. The apparatus includes multiple optical fibers, and each optical fiber has a first end in optical communication with an associated well and a second end in optical communication with an excitation signal source and/or an emission signal detector. The first end of each optical fiber is moveable with respect to the through-hole. A cover is movable between an open position and a closed position relative to the receptacle holder, and the first end of each optical fiber moves with respect to the through-hole of the associated well as the cover moves to the open or closed position or when the cover moves into or out of contact with any receptacles within the wells.


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