The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Apr. 15, 2024
Applicants:

Dna Script, Le Kremlin-Bicêtre, FR;

Institut Pasteur, Paris, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Inventors:

Elise Champion, Paris, FR;

Mikhael Soskine, Franconville, FR;

Thomas Ybert, Paris, FR;

Marc Delarue, Versailles, FR;

Assignees:

DNA Script, Le Kremlin-Bicêtre, FR;

Institut Pasteur, Paris, FR;

Centre National de la Recherche Scientifque, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2005.12); C12N 9/12 (2005.12);
U.S. Cl.
CPC ...
C12N 9/1264 (2012.12); C12N 15/70 (2012.12); C12Y 207/07031 (2012.12);
Abstract

The present invention relates to variants of Terminal deoxynucleotidyl Transferase (TdT), each of which (i) has an amino acid sequence similarity to SEQ ID NO: 2, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33 or 35 with corresponding amino acid substitutions, (ii) is capable of synthesizing a nucleic acid fragment without a template and (iii) is capable of incorporating a modified nucleotide into the nucleic acid fragment.


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