The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Sep. 27, 2019
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Eduardo Da Veiga Beltrame, Pasadena, CA (US);
Jase Gehring, Pasadena, CA (US);
Akshay Tambe, Hayward, CA (US);
Lior S. Pachter, Pasadena, CA (US);
Taleen Dilanyan, Pasadena, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2005.12); C12N 15/11 (2005.12); C12N 15/66 (2005.12); C40B 20/04 (2005.12); C40B 50/14 (2005.12); C40B 70/00 (2005.12);
U.S. Cl.
CPC ...
C12N 15/1065 (2012.12); C12N 15/1096 (2012.12); C12N 15/11 (2012.12); C40B 20/04 (2012.12); C40B 50/14 (2012.12); C40B 70/00 (2012.12);
Abstract
Disclosed herein include methods, compositions, and systems for extending particle-associated oligonucleotides. In some embodiments, the methods of extending particle-associated oligonucleotides enable efficient methods of preparing a library of barcoded beads. It is also provided, in some embodiments, hydrogel beads degradable upon application of a chemical stimulus that comprise releasably attached oligonucleotides.