The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Sep. 26, 2019
Applicant:

Shenzhen Istirbio Co., Ltd., Guangdong, CN;

Inventors:

Yongchao Yao, Guangdong, CN;

Youjia Li, Guangdong, CN;

Sha Yin, Guangdong, CN;

Guangjie Liu, Guangdong, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2005.12); C07K 16/28 (2005.12); C07K 16/30 (2005.12); C40B 30/04 (2005.12);
U.S. Cl.
CPC ...
C12N 15/1037 (2012.12); C07K 16/2803 (2012.12); C07K 16/303 (2012.12); C40B 30/04 (2012.12);
Abstract

Disclosed by the present application are an antibody library construction method and an application thereof. The method comprises the following steps: inserting a first element and a second element into a same vector or different vectors, and transfecting the vectors into the cells to obtain an antibody expression cell library, i.e., the antibody library. The first element comprises CIS activators and selection marker genes; the second element comprises extracellular antibody library coding domain, Notch nuclear structure domain and intracellular transcription structure domain.


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