The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Oct. 16, 2019
Applicant:

Queen Mary University of London, London, GB;

Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2005.12); C12M 1/00 (2005.12); C12M 1/34 (2005.12); C12N 5/071 (2009.12); G01N 33/50 (2005.12);
U.S. Cl.
CPC ...
C12M 21/08 (2012.12); C12M 23/48 (2012.12); C12M 29/00 (2012.12); C12M 29/04 (2012.12); C12M 29/20 (2012.12); C12M 41/14 (2012.12); C12M 41/26 (2012.12); C12M 41/34 (2012.12); C12M 41/44 (2012.12); C12N 5/0698 (2012.12); G01N 33/5088 (2012.12); C12N 2500/02 (2012.12);
Abstract

The invention provides a skin culturing apparatus configured for biphasic culturing of mammalian skin and/or a mammalian skin substitute. The apparatus comprises a first chamber that is configured to provide a gaseous environment having a relative humidity below 90% and comprising less than 5% CO, and a second chamber that is configured to provide tissue culture medium at a temperature of 33.0-37.5° C. and pH of 6.1-7.9. The invention also provides methods for culturing mammalian skin and/or skin substitutes, as well as methods for testing mammalian skin and/or mammalian skin substitutes cultured in the skin culturing apparatus.


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