The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Jun. 03, 2021
Yeda Research and Development Co. Ltd., Rehovot, IL;
Universitat DE Barcelona, Barcelona, ES;
Institució Catalana DE Recerca I Estudis Avançats, Barcelona, ES;
Rony Seger, Rehovot, IL;
Karen Flores, Rehovot, IL;
Xavier Barril Alonso, Barcelona, ES;
Carlos Galdeano Cantador, Barcelona, ES;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Universitat de Barcelona, Barcelona, ES;
Institució Catalana de Recerca I Estudis Avançats, Barcelona, ES;
Abstract
Described herein are compounds having Formula I or Formula II: wherein each dashed line independently represents a saturated or unsaturated bond; Rand R'are aryl or heteroaryl as defined herein; and Rand R′are as defined herein. Further described is a method of inhibiting nuclear translocation of ERK1/2 in a cell, by contacting the cell with a compound having Formula I or Formula II. The compounds may also be for use in treating a disease or disorder associated with nuclear translocation of ERK1/2.