The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Apr. 10, 2023
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Dennis Liotta, Atlanta, GA (US);

Edgars Jecs, Chicago, IL (US);

Yesim Altas Tahirovic, Decatur, GA (US);

Lawrence Wilson, Chamblee, GA (US);

Stephen Pelly, Lilburn, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2005.12); A61K 31/496 (2005.12); C07D 401/04 (2005.12); C07D 401/14 (2005.12); C07D 405/14 (2005.12); C07D 471/08 (2005.12);
U.S. Cl.
CPC ...
C07D 471/08 (2012.12); C07D 401/04 (2012.12); C07D 401/14 (2012.12); C07D 405/14 (2012.12);
Abstract

This disclosure relates to compounds according to Formula (I), salts, prodrugs and pharmaceutical formulation comprising the compound are provided herein for the treatment of CXCR4 and CCR5 related conditions. The conditions may include viral infections, abnormal cellular proliferation, retinal degeneration and inflammatory diseases, or the compounds may be used as immunostimulants or immunosuppressants. Furthermore, the compounds may be used in combination with another active ingredient selected from an antiviral agent or chemotherapeutic agent.


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