The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Jul. 31, 2019
Applicants:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Val-chum, Limited Partnership, Quebec, CA;

Inventors:

Melissa Carey Davies, Arlington, MA (US);

Amos B. Smith, Iii, Merion, PA (US);

Andres Finzi, Quebec, CA;

Shilei Ding, Quebec, CA;

Jean-Philippe Chapleau, Quebec, CA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/96 (2005.12); A61P 31/18 (2005.12); C07D 207/48 (2005.12); C07D 211/56 (2005.12); C07D 211/60 (2005.12); C07D 215/54 (2005.12); C07D 241/04 (2005.12); C07D 265/30 (2005.12); C07D 309/08 (2005.12); C07D 401/12 (2005.12); C07D 403/12 (2005.12); C07D 413/12 (2005.12);
U.S. Cl.
CPC ...
C07D 211/96 (2012.12); A61P 31/18 (2017.12); C07D 207/48 (2012.12); C07D 211/56 (2012.12); C07D 211/60 (2012.12); C07D 215/54 (2012.12); C07D 241/04 (2012.12); C07D 265/30 (2012.12); C07D 309/08 (2012.12); C07D 401/12 (2012.12); C07D 403/12 (2012.12); C07D 413/12 (2012.12);
Abstract

Compounds and methods of treating HIV-1 in a human infected with HIV-1 or preventing HIV-1 infection in a human susceptible to infection with HIV-1 are provided. The compounds are of formula (I), (II), and (IA), wherein R-R, X, X', Y, Y′, Z, and n are defined herein, and the methods comprises administering therapeutically effective amounts of these compounds to the human.


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