The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Oct. 18, 2019
Applicants:

Colorado School of Mines, Golden, CO (US);

The Regents of the University of Colorado, Denver, CO (US);

Inventors:

Frédéric Sarazin, Lakewood, CO (US);

Jeramy Zimmerman, Golden, CO (US);

Rachel Morneau, Los Alamos, NM (US);

Martin Ritter, College Park, MD (US);

David Westerly, Aurora, CO (US);

Quentin Diot, Aurora, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/10 (2005.12); A61K 51/12 (2005.12);
U.S. Cl.
CPC ...
A61N 5/1029 (2012.12); A61K 51/1279 (2012.12);
Abstract

A novel treatment method is disclosed, wherein a patch configured to be placed on a patient's skin is activated, before placement, to deliver localized radiotherapy to a diseased area of the skin. The disclosed devices and methods minimize or prevent collateral damage to the neighboring tissues. In most cases, the disclosed devices and methods include coating a contoured, solid, flexible or conformal substrate with one or more lanthanide elements and then activating (e.g. neutron irradiation) the elements such that its resulting radioisotope emits beta-particles into the diseased skin surface when applied to the patient's skin. Novel processes are described for fabricating and irradiating the lanthanide-based skin patch, for example a holmium-based skin patch.


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