The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Jul. 31, 2019
Applicants:

Taiwan Liposome Co., Ltd., Taipei, TW;

Tlc Biopharmaceuticals, Inc., South San Francisco, CA (US);

Inventors:

Keelung Hong, South San Francisco, CA (US);

Jonathan Fang, South San Francisco, CA (US);

Hao-Wen Kao, South San Francisco, CA (US);

Yi-Yu Lin, South San Francisco, CA (US);

Walter Gwathney, South San Francisco, CA (US);

Assignees:

TAIWAN LIPOSOME CO., LTD., Taipei, TW;

TLC BIOPHARMACEUTICALS, INC., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/1271 (2024.12); A61K 9/00 (2005.12); A61K 31/519 (2005.12); A61K 31/551 (2005.12);
U.S. Cl.
CPC ...
A61K 9/1271 (2012.12); A61K 9/0019 (2012.12); A61K 31/519 (2012.12); A61K 31/551 (2012.12);
Abstract

The present invention relates to a pharmaceutical composition comprising at least one liposome and an antipsychotic drug with a high drug to lipid ratio and encapsulation efficiency. The pharmaceutical composition improves the pharmacokinetic profile and sustains the release of the antipsychotic drug. Also provided is the method for treating schizophrenia or bipolar disorder using the pharmaceutical composition disclosed herein.


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