The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Jun. 25, 2019
Frank Hallock Ebetino, Venice, FL (US);
Shuting Sun, Temple City, CA (US);
Charles E. Mckenna, Pacific Palisades, CA (US);
Keivan Sadrerafi, Pasadena, CA (US);
Philip Cherian, Pasadena, CA (US);
Frank Hallock Ebetino, Venice, FL (US);
Shuting Sun, Temple City, CA (US);
Charles E. McKenna, Pacific Palisades, CA (US);
Keivan Sadrerafi, Pasadena, CA (US);
Philip Cherian, Pasadena, CA (US);
Abstract
Described herein are bisphosphonate oxazolidinone compounds, and conjugates and pharmaceutical formulations thereof, that can include a bisphosphonate and an oxazolidinone (or an oxazolidinone antimicrobial or antibiotic agent, substituent or derivative thereof), where the oxazolidinone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate oxazolidinone compounds, conjugates and pharmaceutical formulations thereof. Also provided herein are methods of use of the compounds, conjugates and formulations for treating a bone disease or for use in preparing a formulation for the treatment a bone disease.