The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Aug. 18, 2021
Applicant:

Nantcell, Inc., Culver City, CA (US);

Inventors:

Adrian Rice, Culver City, CA (US);

Mohit Verma, Culver City, CA (US);

Assignee:

NantCell, Inc., Culver City, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2005.12); C07K 14/005 (2005.12); C07K 14/165 (2005.12); C12N 15/86 (2005.12); A61K 38/00 (2005.12); A61K 39/235 (2005.12); C12N 1/16 (2005.12);
U.S. Cl.
CPC ...
A61K 39/215 (2012.12); C07K 14/005 (2012.12); C07K 14/165 (2012.12); C12N 15/86 (2012.12); A61K 38/00 (2012.12); A61K 39/235 (2012.12); C07K 2317/52 (2012.12); C07K 2319/01 (2012.12); C12N 1/16 (2012.12); C12N 2710/10341 (2012.12); C12N 2770/20034 (2012.12); C12Y 304/17023 (2012.12);
Abstract

Disclosed herein are methods for inducing immunity against a severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV2) in a patient in need thereof. The method comprises administering a vaccine composition comprising a self-adjuvanted SARS-CoV2 Spike (S) RNA-based vaccine (AAHI-SC2), followed by administering a replication defective adenovirus (hAd5) vaccine composition, wherein the adenovirus comprises an E1 gene region deletion and an E2b gene region deletion.


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