The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Nov. 01, 2017
Applicant:
Keio University, Tokyo, JP;
Inventors:
Kenya Honda, Tokyo, JP;
Koji Atarashi, Tokyo, JP;
Seiko Narushima, Tokyo, JP;
Wataru Suda, Tokyo, JP;
Masahira Hattori, Tokyo, JP;
Assignee:
KEIO UNIVERSITY, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2005.12); A61K 39/108 (2005.12); A61K 39/39 (2005.12); A61P 37/04 (2005.12); G01N 33/50 (2005.12); A61K 39/00 (2005.12);
U.S. Cl.
CPC ...
A61K 39/0266 (2012.12); A61K 39/39 (2012.12); A61P 37/04 (2017.12); G01N 33/5044 (2012.12); A61K 2039/52 (2012.12); A61K 2039/57 (2012.12);
Abstract
The result of orally administering saliva derived from a Crohn's disease patient or an ulcerative colitis patient to germ-free mice has revealed that Th1 cells markedly increased in the colons. Further, from the bacterial microbiota in the intestines of the mice in which such an increase in Th1 cells were observed, bacteria have been successfully isolated which caused strong Th1 cell induction in the colon upon intestinal colonization.