The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Aug. 20, 2015
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Liangfang Zhang, San Diego, CA (US);
Che-Ming Jack Hu, San Diego, CA (US);
Jonathan Copp, Cleveland, OH (US);
Ronnie H. Fang, Irvine, CA (US);
Brian T. Luk, Irvine, CA (US);
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2005.12); A61K 9/00 (2005.12); A61K 9/51 (2005.12); A61K 35/12 (2014.12); A61K 39/385 (2005.12); A61K 45/06 (2005.12); A61K 47/34 (2016.12);
U.S. Cl.
CPC ...
A61K 39/0008 (2012.12); A61K 9/0014 (2012.12); A61K 9/0019 (2012.12); A61K 9/5146 (2012.12); A61K 9/5184 (2012.12); A61K 35/12 (2012.12); A61K 39/385 (2012.12); A61K 45/06 (2012.12); A61K 47/34 (2012.12); A61K 2039/55555 (2012.12); A61K 2039/6006 (2012.12);
Abstract
The invention provides a composition, and method of use thereof, comprising self-antigen displaying nanoparticles to target auto-reactive immune components for treating and/or preventing the autoimmune diseases associated therewith. The nanoparticles can also be loaded with cytotoxic drugs for targeted cell killing or with immune-tolerizing compounds to normalize the immune regulation.