The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Jul. 26, 2023
Glaxosmithkline Intellectual Property Development Limited, Stevenage, GB;
Andrew B. Benowitz, Stevenage, GB;
David T. Fosbenner, Collegeville, PA (US);
Bryan Wayne King, Collegeville, PA (US);
Stuart Paul Romeril, Collegeville, PA (US);
Megan Ketchum, Collegeville, PA (US);
Todd Koretke, Collegeville, PA (US);
Elizabeth Ann Moroz, Collegeville, PA (US);
Grace Price, Collegeville, PA (US);
Abstract
The invention relates to substituted pyridine derivatives that are inhibitors of the activity of DNA methyltransferase 1 (DNMT1). The invention also relates to pharmaceutical compositions comprising such compounds and methods of using such compounds in the treatment of cancer, pre-cancerous syndromes, beta haemoglobinopathy disorders, and other diseases associated with inappropriate DNMT1 activity.