The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2025

Filed:

Apr. 26, 2021
Applicants:

The Research Foundation for the State University of New York, Binghamton, NY (US);

Rosalind Franklin University of Medicine and Science, North Chicago, IL (US);

Board of Trustees of Michigan State University, East Lansing, MI (US);

Inventors:

Christopher Roy Bishop, Vestal, NY (US);

Anthony West, North Chicago, IL (US);

Fredric Manfredsson, Grand Rapids, MI (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2005.12); A61K 9/00 (2005.12); A61K 31/05 (2005.12); A61K 31/13 (2005.12); A61K 31/198 (2005.12); A61K 31/4545 (2005.12); A61K 31/495 (2005.12); A61K 31/55 (2005.12); A61K 45/06 (2005.12); A61P 25/16 (2005.12);
U.S. Cl.
CPC ...
A61K 31/496 (2012.12); A61K 9/0053 (2012.12); A61K 31/05 (2012.12); A61K 31/13 (2012.12); A61K 31/198 (2012.12); A61K 31/4545 (2012.12); A61K 31/495 (2012.12); A61K 31/55 (2012.12); A61K 45/06 (2012.12); A61P 25/16 (2017.12);
Abstract

A method of treating and attenuating L-DOPA-induced dyskinesia, comprising administering an effective dose of at least one pharmacological agent, e.g., vilazodone, having serotonin-specific reuptake inhibition (SSRI) and serotonin receptor 1A (5-HT1AR) partial agonism activity, in conjunction with L-DOPA. Other agents, such as an L-DOPA decarboxylase inhibitor, e.g., carbidopa, or other adjunct treatments may also be provided.


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