The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Aug. 29, 2024
University of Jeddah, Jeddah, SA;
Roaa M. Alreemi, Jeddah, SA;
Hind A. Alkhatabi, Jeddah, SA;
Abdelsattar M. Omar, Jeddah, SA;
Mohammed A. Baradwan, Jeddah, SA;
Yosra A. Muhammad, Jeddah, SA;
Peter Natesan Pushparaj, Jeddah, SA;
Mohammad Basabrain, Jeddah, SA;
Moustafa E. El-Araby, Richmond, VA (US);
University of Jeddah, Jeddah, SA;
King Abdulaziz University, Jeddah, SA;
Abstract
Three compounds having a common molecular template of 2-(5-(N-acylamino)pyridin-2-yl)-N-benzylacetamide (Compounds I, II and I) are identified as potential anticancer therapeutic agents, and for the treatment of Acute Myeloid Leukemia (AML) in particular. Compound I was specifically designed to target AML cells, inhibit growth, and induce cell death. Compound I demonstrated a dose-dependent effect on AML cell lines HL-60, Mv4-11, KG-1a, and K562.