The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2025
Filed:
Feb. 28, 2022
Applicant:
Salix Pharmaceuticals, Inc., Bridgewater, NJ (US);
Inventors:
William Forbes, Raleigh, NC (US);
Kunal Merchant, Durham, NC (US);
Enoch Bortey, Chapel Hill, NC (US);
Audrey Shaw, Durham, NC (US);
Assignee:
Salix Pharmaceuticals, Inc., Bridgewater, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2005.12); A61K 31/7016 (2005.12); A61K 45/06 (2005.12); G16H 20/10 (2017.12);
U.S. Cl.
CPC ...
A61K 31/437 (2012.12); A61K 31/7016 (2012.12); A61K 45/06 (2012.12); G16H 20/10 (2017.12); Y02A 90/10 (2017.12);
Abstract
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin. The instant application also provides methods for determining if a subject has a neurological condition or hepatic encephalopathy by determining the critical flicker frequency and/or the venous ammonia level of the subject at two or more time points. The invention further provides methods for treating these subjects.