The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2025

Filed:

Jun. 16, 2020
Applicant:

Fluidigm Canada Inc., Markham, CA;

Inventors:

Paul Corkum, Markham, CA;

Alexander Loboda, Markham, CA;

David M. Rayner, Markham, CA;

Assignee:

Fluidigm Canada Inc., Markham, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/14 (2023.12); G01N 15/10 (2023.12); H01J 49/00 (2005.12); H01J 49/04 (2005.12); H01J 49/16 (2005.12);
U.S. Cl.
CPC ...
H01J 49/0004 (2012.12); G01N 15/14 (2012.12); H01J 49/0463 (2012.12); H01J 49/164 (2012.12); G01N 2015/1006 (2012.12);
Abstract

Embodiments of the present invention relate to replacement of the previous ICP-based ionisation system with a new laser ionisation system, providing improved mass spectrometer-based apparatus and methods for using them to analyse samples, in particular the use of mass spectrometry mass cytometry, imaging mass spectrometry and imaging mass cytometry, for the analysis of biological samples. Accordingly, embodiments of the present invention provide an apparatus, for example a mass cytometer, comprising: 1) a sampler; 2) a laser ionisation system to receive material removed from the sample by the sampler, wherein the laser ionisation system comprises an ionisation system conduit and a pulsed laser adapted to ionise sample material passing through or exiting the ionisation system conduit; and 3) a mass spectrometer to receive elemental ions from said ionisation system and to analyse said elemental ions.


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