The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Nov. 17, 2016
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Cigall Kadoch, Tiburon, CA (US);
Gabriel Sandoval, Lemont, IL (US);
William C. Hahn, Newton, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2005.12); G01N 33/50 (2005.12); G01N 33/53 (2005.12); G01N 33/574 (2005.12); G01N 33/68 (2005.12);
U.S. Cl.
CPC ...
G01N 33/5011 (2012.12); G01N 33/57434 (2012.12); G01N 33/6875 (2012.12); G01N 2333/4703 (2012.12); G01N 2500/02 (2012.12);
Abstract
The present invention provides methods of screening for compounds that interfere with the interaction between ERG. ETV1, ETV4 or ETV5 and mSWI/SNF (BAF) chromatin remodeling complex proteins. Included are methods of screening for compounds that interfere with the interaction between ERG, ETV1, ETV4 or ETV5 and BAF155. Methods of treating prostate cancer with compounds that interfere with the interaction between ERG, ETV1, ETV4 or ETV5 and mSWI/SNF (BAF) chromatin remodeling complex proteins are also provided.