The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Jun. 02, 2019
Applicant:
Children's National Medical Center, Washington, DC (US);
Inventors:
Christopher Heier, Washington, DC (US);
Alyson Fiorillo, Washington, DC (US);
Assignee:
Children's National Medical Center, Washington, DC (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2009.12); A61K 31/573 (2005.12); A61K 31/7088 (2005.12); A61P 21/00 (2005.12); C12Q 1/68 (2017.12);
U.S. Cl.
CPC ...
C12N 15/113 (2012.12); A61K 31/573 (2012.12); A61K 31/7088 (2012.12); A61P 21/00 (2017.12); C12N 2310/11 (2012.12); C12N 2320/31 (2012.12); C12N 2320/35 (2012.12);
Abstract
The present disclosure relates to compositions comprising an antisense RNA sequence comprising a region of complementarity that is substantially complementary to an miRNA. Pharmaceutical compositions comprising the antisense RNA molecule, optionally further comprising an anti-inflammatory corticosteroid are also disclosed. Methods of treating or preventing inflammation, a steroid side effect, or a muscle disease using the one or the pharmaceutical compositions are also disclosed.