The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2025

Filed:

Dec. 21, 2023
Applicant:

Avita Medical Americas, Llc, Valencia, CA (US);

Inventors:

Niraj Kumar Doshi, Valencia, CA (US);

Jugal Kapadia, Valencia, CA (US);

Matthew Krywcun, Laguna Niguel, CA (US);

David Allen Fencil, Valencia, CA (US);

David Melbye, Valencia, CA (US);

Katie Bush, Marblehead, MA (US);

Carl Swindle, San Clemente, CA (US);

Paul Faucher, San Diego, CA (US);

Matthew Richard Johnson, San Diego, CA (US);

Adam Livingston, San Diego, CA (US);

Michael MacCollum, San Diego, CA (US);

Evan Misuraca, San Diego, CA (US);

Kyle Stewart, San Diego, CA (US);

Mikhail Tikh, San Diego, CA (US);

Austin Wolf, San Diego, CA (US);

Assignee:

AVITA Medical Americas, LLC, Valencia, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/36 (2005.12); B01L 3/00 (2005.12); C12M 1/00 (2005.12); C12M 1/02 (2005.12); C12M 1/12 (2005.12); C12M 1/26 (2005.12); C12M 1/32 (2005.12); C12M 3/00 (2005.12); C12M 3/02 (2005.12); C12M 3/04 (2005.12); C12M 3/08 (2005.12); G01N 1/28 (2005.12);
U.S. Cl.
CPC ...
C12M 41/48 (2012.12); B01L 3/50255 (2012.12); C12M 3/02 (2012.12); C12M 3/08 (2012.12); C12M 21/08 (2012.12); C12M 23/12 (2012.12); C12M 23/38 (2012.12); C12M 23/42 (2012.12); C12M 23/50 (2012.12); C12M 25/04 (2012.12); C12M 27/10 (2012.12); C12M 33/00 (2012.12); C12M 33/14 (2012.12); C12M 41/18 (2012.12); G01N 1/286 (2012.12); B01L 2300/042 (2012.12); G01N 2001/2866 (2012.12);
Abstract

One or more systems for automated preparation of a regenerative epidermal suspension comprises a base unit, a cartridge assembly containing a cup, and a tissue disaggregator. The system may also include related tools. The system executes one or more sequences wherein a first motor actuates the pestle against a tissue sample that is disposed along a screen within the cup while the tissue sample is in contact with, in sequence, an enzyme solution, a first buffer solution, and then a second buffer solution. To transition between fluidic contact stages or steps, the tissue disaggregator engages with and lifts the cup into a raised position within a processing area of the cartridge while a base plate motor rotates the appropriate well into alignment under the cup for each processing step. Once the sequence is complete, a user may draw up a regenerative epidermal suspension through an opening in the cartridge top cover.


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