The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Sep. 02, 2020
Amgen Inc., Thousand Oaks, CA (US);
Amgen Research (Munich) Gmbh, Munich, DE;
Peter Kufer, Munich, DE;
Tobias Raum, Munich, DE;
Patrick Hoffmann, Munich, DE;
Roman Kischel, Munich, DE;
Ralf Lutterbuese, Munich, DE;
Doris Rau, Munich, DE;
Paul Adam, Munich, DE;
Eric Borges, Munich, DE;
Barbara Hebeis, Munich, DE;
Susanne Hipp, Munich, DE;
Amgen Inc., Thousand Oaks, CA (US);
Amgen Research (Munich) GmbH, Munich, DE;
Abstract
The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster 3 of BCMA, and the second binding domain is capable of binding to the T cell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.