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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12281167 B1

PDFFull Text
Date of Patent:
Apr. 21, 2025

Filed:

Sep. 26, 2023

Humanized anti-gdnf family alpha-receptor 4 (grf-alpha-4) antibodies and chimeric antigen receptors (cars)

Applicants:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Donald L. Siegel, Lansdale, PA (US);

Vijay Bhoj, Philadelphia, PA (US);

Christoph Rader, Jupiter, FL (US);

Rebecca Goydel, La Jolla, CA (US);

Assignees:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Attorneys:

Saul Ewing LLP

Kathryn Doyle

Alireza Behrooz

Primary Examiner:

Scarlett Y Goon

Assistant Examiner:

Audrey L Buttice

Int. Cl.
CPC ...
C07K 16/28 (2005.12); A61K 39/00 (2005.12); A61P 35/00 (2005.12); C07K 14/705 (2005.12); C07K 14/725 (2005.12);
U.S. Cl.
CPC ...
C07K 16/2863 (2012.12); A61K 39/4611 (2023.04); A61K 39/4631 (2023.04); A61K 39/46432 (2023.04); A61K 39/464412 (2023.04); A61P 35/00 (2017.12); C07K 14/7051 (2012.12); C07K 14/70517 (2012.12); C07K 14/70578 (2012.12); A61K 2039/505 (2012.12); A61K 2239/28 (2023.04); A61K 2239/31 (2023.04); A61K 2239/38 (2023.04); A61K 2239/48 (2023.04); C07K 2317/24 (2012.12); C07K 2317/622 (2012.12); C07K 2319/02 (2012.12); C07K 2319/03 (2012.12);
Abstract

The present invention relates to compositions and methods for treating diseases, disorders or conditions associated with the expression of the glycosyl-phosphatidylinositol (GPI)-linked GDNF family protein α-receptor 4 (GFRα4).

Find Patent Forward Citations

Siegel, Donald. (2025). Humanized anti-gdnf family alpha-receptor 4 (grf-alpha-4) antibodies and chimeric antigen receptors (cars) (U.S. Patent No. 12281167). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12281167

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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