The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Sep. 29, 2020
Applicant:
Jiangsu Alphamab Biopharmaceuticals Co., Ltd., Jiangsu, CN;
Inventors:
Ting Xu, Suzhou, CN;
Kangping Guo, Suzhou, CN;
Dong Yang, Suzhou, CN;
Pilin Wang, Suzhou, CN;
Yuhao Jin, Suzhou, CN;
Xiaoxiao Wang, Suzhou, CN;
Assignee:
JIANGSU ALPHAMAB BIOPHARMACEUTICALS CO., LTD., Suzhou, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2005.12); A61K 39/395 (2005.12); A61P 35/00 (2005.12); A61K 39/00 (2005.12);
U.S. Cl.
CPC ...
C07K 16/2818 (2012.12); C07K 16/2827 (2012.12); A61K 2039/505 (2012.12); C07K 2317/52 (2012.12);
Abstract
The present disclosure provides a dimer formed by two polypeptide chains, with each of the two polypeptide chains comprising an antibody Fc subunit, wherein the dimer comprises two or more immunoglobulin single variable domains (ISVDs), at least one of the ISVDs is specific for PD-L1, and at least one of the ISVDs is specific for CTLA4.