The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
May. 20, 2020
Voronoi Inc., Incheon, KR;
Voronoibio Inc., Incheon, KR;
Seo Hyun Jo, Seoul, KR;
Hua Li, Incheon, KR;
Hee Sun Ryu, Incheon, KR;
Hwan Kim, Seoul, KR;
Ji Yoon Seok, Incheon, KR;
Sun Hwa Lee, Incheon, KR;
Jung Beom Son, Incheon, KR;
Nam Doo Kim, Incheon, KR;
VORONOI Inc., Incheon, KR;
VORONOIBIO Inc., Incheon, KR;
Abstract
The present invention relates to an N-containing heteroaryl derivative and a pharmaceutical composition comprising same as an active ingredient for the prevention or treatment of cancer. The derivative exhibits high inhibitory activity against various protein kinases, particularly excellent ret proto-oncogene (RET) enzyme inhibitory ability, and has an excellent effect of inhibiting the proliferation of medullary thyroid cancer cells and lung cancer cells, which express RET fusion genes, and thus the derivative can be effectively used in the treatment of cancer, for example, medullary thyroid cancer or lung cancer, and particularly, can be effectively used in the treatment of cancer in which RET fusion genes are expressed.