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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12281109 B1

PDFFull Text
Date of Patent:
Apr. 21, 2025

Filed:

Mar. 29, 2020

Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes

Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Jian Liu, Edison, NJ (US);

Younong Yu, East Brunswick, NJ (US);

Joseph A. Kozlowski, Princeton, NJ (US);

Deyou Sha, Yardley, PA (US);

Wensheng Yu, Edison, NJ (US);

Joseph M. Kelly, Parlin, NJ (US);

Scott E. Wolkenberg, Wyndmoor, PA (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:

Eric Greenwald

John C. Todaro

Primary Examiner:

Sun Jae Yoo

Int. Cl.
CPC ...
A61P 25/28 (2005.12); A61P 29/00 (2005.12); A61P 31/18 (2005.12); A61P 35/00 (2005.12); C07D 401/14 (2005.12); C07D 405/14 (2005.12); C07D 417/12 (2005.12); C07D 417/14 (2005.12); C07D 487/04 (2005.12);
U.S. Cl.
CPC ...
C07D 417/12 (2012.12); C07D 401/14 (2012.12); C07D 405/14 (2012.12); C07D 417/14 (2012.12); C07D 487/04 (2012.12);
Abstract

The present invention relates to Compounds of Formula I: and pharmaceutically acceptable salts or prodrug thereof, wherein R, R, R, A and B are as defined herein. The present invention also relates to compositions comprising at least one compound of Formula I, and methods of using the compounds of Formula I for treating or preventing cancer, inflammation, neurodegeneration disease and/or diabetes in a subject.

Find Patent Forward Citations

Liu, Jian. (2025). Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes (U.S. Patent No. 12281109). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12281109

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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