The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Oct. 21, 2020
Applicants:
Ayala Pharmaceuticals Inc., Wilmington, DE (US);
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Matti Davis, Modiin, IL;
Bruce S. Fischer, East Brunswick, NJ (US);
Gaurav Bajaj, Plainsboro, NJ (US);
Assignees:
Immunome, Inc., Bothell, WA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 243/14 (2005.12); A61K 9/00 (2005.12); A61K 31/203 (2005.12); A61K 31/44 (2005.12); A61K 31/5513 (2005.12); A61K 31/635 (2005.12); A61K 39/395 (2005.12); A61P 35/00 (2005.12);
U.S. Cl.
CPC ...
C07D 243/14 (2012.12); A61K 9/0019 (2012.12); A61K 9/0053 (2012.12); A61K 31/203 (2012.12); A61K 31/44 (2012.12); A61K 31/5513 (2012.12); A61K 31/635 (2012.12); A61K 39/3955 (2012.12); A61P 35/00 (2017.12);
Abstract
The present invention provides compositions comprising bisfluoroalkyl-1,4-benzodiazepinone compounds, including compounds of Formula (I) or prodrugs thereof; in combination with an additional cancer therapeutic agent, and methods of use thereof for treating diseases and disorders such as cancer.