The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2025

Filed:

Mar. 18, 2020
Applicant:

Lead Discovery Center Gmbh, Dortmund, DE;

Inventors:

Raffaella Di Lucrezia, Wuppertal, DE;

Tim Bergbrede, Dortmund, DE;

Peter Nussbaumer, Dortmund, DE;

Peter Schröder, Dortmund, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/20 (2005.12); A61K 31/4375 (2005.12); A61K 31/438 (2005.12); A61K 31/4545 (2005.12); A61K 31/47 (2005.12); A61K 31/4709 (2005.12); A61K 31/496 (2005.12); A61K 31/5377 (2005.12); A61K 45/06 (2005.12); A61P 35/00 (2005.12); C07D 401/12 (2005.12); C07D 409/14 (2005.12); C07D 471/04 (2005.12); C07D 471/10 (2005.12); C07D 491/107 (2005.12); C07D 519/00 (2005.12);
U.S. Cl.
CPC ...
C07D 215/20 (2012.12); A61K 31/4375 (2012.12); A61K 31/438 (2012.12); A61K 31/47 (2012.12); A61K 31/4709 (2012.12); A61K 31/5377 (2012.12); A61K 45/06 (2012.12); A61P 35/00 (2017.12); C07D 401/12 (2012.12); C07D 471/04 (2012.12); C07D 471/10 (2012.12); C07D 491/107 (2012.12); C07D 519/00 (2012.12);
Abstract

The present invention relates to compounds of the general formula (I): (I), wherein V, W, M, R, R and Y have the designations cited below, or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof, and to processes for the preparation of compounds of the general formula (I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof. The invention also relates to compounds of the general formula (I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof for use as a medicament. Further, the invention relates to compounds of the general formula (I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof for use in the treatment of cancer. Moreover, the invention relates to compounds of the general formula (I) or a pharmaceutically or veterinary acceptable salt, hydrate or solvate thereof for treating cancer in simultaneous, alternating or subsequent combination with another cancer therapy.


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