The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2025

Filed:

Aug. 29, 2022
Applicant:

Cytosorbents, Inc., Princeton, NJ (US);

Inventors:

Phillip P. Chan, Cherry Hill, NJ (US);

Vincent J. Capponi, Lawrenceville, NJ (US);

Thomas D. Golobish, Princeton, NJ (US);

Humayra Begum Ali, Princeton, NJ (US);

Assignee:

CytoSorbents, Inc., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/36 (2005.12); A61K 9/16 (2005.12); A61K 31/765 (2005.12); B01J 20/26 (2005.12); B01J 20/28 (2005.12); C08F 299/00 (2005.12); C08J 9/26 (2005.12);
U.S. Cl.
CPC ...
A61M 1/3679 (2012.12); A61K 9/16 (2012.12); A61K 31/765 (2012.12); B01J 20/261 (2012.12); B01J 20/28069 (2012.12); B01J 20/28078 (2012.12); C08F 299/00 (2012.12); C08J 9/26 (2012.12); A61M 2202/0057 (2012.12); A61M 2202/0405 (2012.12); A61M 2202/0413 (2012.12); A61M 2202/0415 (2012.12); A61M 2202/0423 (2012.12); A61M 2202/0464 (2012.12); A61M 2202/0466 (2012.12); A61M 2202/049 (2012.12); A61M 2202/0492 (2012.12); A61M 2202/0496 (2012.12); A61M 2202/20 (2012.12); A61M 2202/203 (2012.12); A61M 2202/206 (2012.12); C08J 2201/0444 (2012.12); C08J 2207/10 (2012.12); C08J 2353/00 (2012.12);
Abstract

Provided herein are materials and methods of reducing contamination in a biological substance or treating contamination in a subject by one or more toxins comprising contacting the biological substance with an effective amount of a sorbent capable of sorbing the toxin, wherein the sorbent comprises a plurality of pores ranging from 50 Å to 40,000 Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and sorbing the toxin. Also provided are kits to reduce contamination by one or more toxins in a biological substance comprising a sorbent capable of sorbing a toxin, wherein the sorbent comprises a plurality of pores ranging from 50 Å to 40,000 Å with a pore volume of 0.5 cc/g to 5.0 cc/g and a size of 0.05 mm to 2 cm and a vessel to store said sorbent when not in use together with packaging for same.


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