The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Nov. 23, 2021
Applicant:
Xilio Development, Inc., Waltham, MA (US);
Inventors:
Raphael Rozenfeld, Swampscott, MA (US);
Ugur Eskiocak, Somerville, MA (US);
Huawei Qiu, Westborough, MA (US);
Parker Johnson, Allston, MA (US);
Kurt Allen Jenkins, Weymouth, MA (US);
Magali Pederzoli-Ribeil, Cambridge, MA (US);
Dheeraj Singh Tomar, Dorchester, MA (US);
Rebekah Kay O'Donnell, Brookline, MA (US);
Assignee:
Xilio Development, Inc., Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/65 (2016.12); A61K 38/20 (2005.12); A61K 47/64 (2016.12); A61P 35/00 (2005.12);
U.S. Cl.
CPC ...
A61K 47/65 (2017.07); A61K 38/2013 (2012.12); A61K 38/208 (2012.12); A61K 38/2086 (2012.12); A61K 47/64 (2017.07); A61P 35/00 (2017.12);
Abstract
The present disclosure provides tumor-specific cleavable linkers and their use in drugs and prodrugs for delivering therapeutics to a tumor cell environment. The present disclosure also provides cleavage products of said drugs and prodrugs, and methods related to the use of the same.