The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
May. 01, 2024
Applicant:
Avilar Therapeutics, Inc., Waltham, MA (US);
Inventors:
Mark George Saulnier, Higganum, CT (US);
Jesse Jingyang Chen, Lexington, MA (US);
Srinivasa Karra, Pembrooke, MA (US);
Kevin Tyler Sprott, Needham, MA (US);
Jason Allan Wiles, Madison, CT (US);
Soumya Ray, Quincy, MA (US);
Assignee:
AVILAR THERAPEUTICS, INC., Waltham, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/54 (2016.12); A61K 47/62 (2016.12); C07H 5/06 (2005.12); C07H 7/02 (2005.12); C07H 9/02 (2005.12); C07H 9/04 (2005.12); C07H 15/203 (2005.12); C07H 17/00 (2005.12); C07H 17/02 (2005.12); C07H 19/02 (2005.12); C07H 19/044 (2005.12); H03L 7/081 (2005.12); H03L 7/099 (2005.12);
U.S. Cl.
CPC ...
A61K 47/549 (2017.07); A61K 47/62 (2017.07); C07H 5/06 (2012.12); C07H 7/02 (2012.12); C07H 9/02 (2012.12); C07H 9/04 (2012.12); C07H 15/203 (2012.12); C07H 17/00 (2012.12); C07H 17/02 (2012.12); C07H 19/02 (2012.12); C07H 19/044 (2012.12); H03L 7/0814 (2012.12); H03L 7/0818 (2012.12); H03L 7/0998 (2012.12);
Abstract
Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.