The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Oct. 17, 2019
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Vanderbilt University, Nashville, TN (US);
David A. Vorp, Pittsburgh, PA (US);
Aneesh Krishna Ramaswamy, Pittsburgh, PA (US);
Justin Sol Weinbaum, Allison Park, PA (US);
Kory James Blose, Pittsburgh, PA (US);
Timothy Kwang-Joon Chung, Pittsburgh, PA (US);
Trevor Kickliter, Allentown, PA (US);
Yogev Baruch, Pittsburgh, PA (US);
John A. Curci, Nashville, TN (US);
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Vanderbilt University, Nashville, TN (US);
Abstract
A method of delivering cells to a target tissue is provided comprising depositing a hydrogel pre-gel comprising magnetic particle-loaded cells to the target tissue and, prior to or during gelation of the hydrogel, drawing the magnetic particle-loaded cells to the tissue with a magnetic field, followed by gelation of the hydrogel to lock the cells in place on the tissue. The cells may be mesenchymal stem cells, such as adipose-derived mesenchymal stem cells, and the target tissue may be adventitial tissue of an aneurysm in a blood vessel. Also provided are devices useful in the method.