The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Oct. 30, 2023
Applicant:
Rnaimmune, Inc., Gaithersburg, MD (US);
Inventors:
David Brown, Gaithersburg, MD (US);
Yong-Sik Bong, Frederick, MD (US);
Neeti Ananthaswamy, Potomac, MD (US);
Naihsuan C. Guy, Gaithersburg, MD (US);
Dong Shen, Baltimore, MD (US);
Assignee:
RNAIMMUNE, INC., Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2005.12); A61K 9/51 (2005.12); A61K 45/06 (2005.12); A61P 31/14 (2005.12); C07K 14/005 (2005.12); A61K 39/00 (2005.12);
U.S. Cl.
CPC ...
A61K 39/215 (2012.12); A61K 9/5123 (2012.12); A61K 45/06 (2012.12); A61P 31/14 (2017.12); C07K 14/005 (2012.12); A61K 2039/6018 (2012.12); A61K 2039/6031 (2012.12);
Abstract
Provided herein is a ribonucleic acid (RNA) encoding a spike (S) protein or an immunogenic fragment thereof of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) comprising at least one non-naturally occurring amino acid mutation. In some embodiments, the S protein is derived from an Omicron variant. Additionally provided are relevant polynucleotides, vectors, cells, compositions, kits, production methods and methods of use.