The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Dec. 28, 2017
Applicant:
Trustees of Tufts College, Medford, MA (US);
Inventors:
David L. Kaplan, Concord, MA (US);
Fiorenzo G. Omenetto, Lexington, MA (US);
Assignee:
Trustees of Tufts College, Medford, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/20 (2005.12); A61K 9/00 (2005.12); A61K 9/06 (2005.12); A61K 9/14 (2005.12); A61K 9/19 (2005.12); A61K 9/50 (2005.12); A61K 9/70 (2005.12); A61K 38/00 (2005.12); A61K 39/00 (2005.12); A61K 39/02 (2005.12); A61K 39/04 (2005.12); A61K 39/08 (2005.12); A61K 39/09 (2005.12); A61K 39/095 (2005.12); A61K 39/12 (2005.12); A61K 39/165 (2005.12); A61K 47/42 (2016.12); A61K 47/46 (2005.12); B82Y 5/00 (2010.12);
U.S. Cl.
CPC ...
A61K 39/20 (2012.12); A61K 9/0019 (2012.12); A61K 9/06 (2012.12); A61K 9/146 (2012.12); A61K 9/19 (2012.12); A61K 9/5026 (2012.12); A61K 9/5063 (2012.12); A61K 9/7007 (2012.12); A61K 39/0015 (2012.12); A61K 39/02 (2012.12); A61K 39/04 (2012.12); A61K 39/08 (2012.12); A61K 39/092 (2012.12); A61K 39/095 (2012.12); A61K 39/099 (2012.12); A61K 39/12 (2012.12); A61K 39/165 (2012.12); A61K 47/42 (2012.12); A61K 47/46 (2012.12); B82Y 5/00 (2012.12); A61K 38/00 (2012.12); A61K 2039/5252 (2012.12); A61K 2039/5254 (2012.12); A61K 2039/6031 (2012.12); A61K 2039/622 (2012.12); A61K 2039/64 (2012.12); A61K 2039/70 (2012.12); C12N 2760/18434 (2012.12); C12N 2760/18734 (2012.12); C12N 2770/36234 (2012.12); Y02A 50/30 (2017.12);
Abstract
Provided herein are methods and compositions for stabilization of active agents. The active agents are distributed, mixed or embedded in a silk fibroin matrix, thereby retaining the bioactivity of the active agents upon storage and/or transportation. In some embodiments, the storage-stable vaccine-silk compositions are also provided herein.