The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Apr. 22, 2019
Applicants:
Michael S Tempesta, El Granada, CA (US);
F. Joseph Daugherty, Omaha, NE (US);
Inventors:
Michael S Tempesta, El Granada, CA (US);
F. Joseph Daugherty, Omaha, NE (US);
Assignee:
Phenolics, LLC, Omaha, NE (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/664 (2005.12); A61K 9/00 (2005.12); A61K 9/50 (2005.12); A61K 31/205 (2005.12); A61K 47/10 (2016.12); A61K 47/40 (2005.12);
U.S. Cl.
CPC ...
A61K 31/664 (2012.12); A61K 9/0053 (2012.12); A61K 9/5026 (2012.12); A61K 31/205 (2012.12); A61K 47/10 (2012.12); A61K 47/40 (2012.12);
Abstract
Formulations of creatine, preferably phosphocreatine and most preferably disodium phosphocreatine, combined with cyclodextrin exhibit improved uptake across digestive mucosa, including intestinal, esophageal, and stomach mucosa. In particular, the formulations of the present invention are designed for protection of the cyclodextrin as it comes in contact with gastric juices so as to allow thereafter for unexpectedly improved site-specific intestinal release.