The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Jun. 19, 2019
Applicant:
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Inventors:
Jerold Chun, La Jolla, CA (US);
William J. Romanow, La Jolla, CA (US);
Ming-Hsiang Lee, La Jolla, CA (US);
Victoria Blaho, La Jolla, CA (US);
Assignee:
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2005.12); A61K 31/13 (2005.12); A61K 31/27 (2005.12); A61K 31/445 (2005.12); A61K 31/496 (2005.12); A61K 31/505 (2005.12); A61K 31/513 (2005.12); A61K 31/538 (2005.12); A61K 31/55 (2005.12); A61K 31/7072 (2005.12); A61K 45/06 (2005.12); A61P 25/28 (2005.12); C12Q 1/6883 (2017.12); G01N 33/68 (2005.12);
U.S. Cl.
CPC ...
A61K 31/551 (2012.12); A61K 31/13 (2012.12); A61K 31/27 (2012.12); A61K 31/445 (2012.12); A61K 31/496 (2012.12); A61K 31/505 (2012.12); A61K 31/513 (2012.12); A61K 31/538 (2012.12); A61K 31/55 (2012.12); A61K 31/7072 (2012.12); A61K 45/06 (2012.12); A61P 25/28 (2017.12); C12Q 1/6883 (2012.12); G01N 33/6896 (2012.12); G01N 2800/2821 (2012.12);
Abstract
Described herein are methods for inhibiting generation of one or more non-classical variant(s) of amyloid precursor protein (APP) gene. Provided herein are methods for diagnosing an individual having or suspected of having Alzheimer's-disease following identification of an expression profile or an activity profile of the one or more non-classical variant(s) and treating the individual using a reverse transcriptase inhibitor or salt thereof.