The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Jul. 17, 2019
Applicant:
Wista Laboratories Ltd., Singapore, SG;
Inventors:
Claude Michel Wischik, Aberdeen, GB;
Björn Olaf Schelter, Aberdeen, GB;
Helen Christine Shiells, Aberdeen, GB;
Assignee:
WisTa Laboratories Ltd., Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5415 (2005.12); A23L 33/00 (2015.12); A23L 33/105 (2015.12); A23L 33/15 (2015.12); A23L 33/175 (2015.12); A23L 33/29 (2015.12); A61K 9/00 (2005.12); A61K 9/20 (2005.12); A61K 9/48 (2005.12); A61K 31/13 (2005.12); A61P 25/28 (2005.12);
U.S. Cl.
CPC ...
A61K 31/5415 (2012.12); A23L 33/105 (2016.07); A23L 33/15 (2016.07); A23L 33/175 (2016.07); A23L 33/29 (2016.07); A23L 33/30 (2016.07); A61K 9/0053 (2012.12); A61K 9/20 (2012.12); A61K 9/48 (2012.12); A61K 31/13 (2012.12); A61P 25/28 (2017.12);
Abstract
The invention provides novel dosing regimens for Leuco-Methylthioninium (LMT) compounds which maximise the proportion of subjects in which the MT concentration will exceed concentrations in which therapeutic efficacy in relation to treatment of neurodegenerative disorders such as Alzheimer's disease and rontotemporal dementias can be achieved, while maintaining a desirable clinical profile. Also provided are LMT-containing dosage units and other compositions.