The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
May. 23, 2022
Applicant:
Mirati Therapeutics, Inc., San Diego, CA (US);
Inventors:
Jacob Haling, San Diego, CA (US);
John Michael Ketcham, Carlsbad, CA (US);
Shilpi Khare, San Diego, CA (US);
Assignee:
MIRATI THERAPEUTICS, INC., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2005.12); A61K 31/502 (2005.12); A61K 31/5025 (2005.12); A61K 31/506 (2005.12); A61K 31/5377 (2005.12); A61K 31/5383 (2005.12); A61P 11/00 (2005.12); A61P 35/00 (2005.12);
U.S. Cl.
CPC ...
A61K 31/519 (2012.12); A61K 31/502 (2012.12); A61K 31/5025 (2012.12); A61K 31/506 (2012.12); A61K 31/5377 (2012.12); A61K 31/5383 (2012.12); A61P 11/00 (2017.12); A61P 35/00 (2017.12);
Abstract
The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a SOS1 inhibitor and a KRas G12C inhibitor, pharmaceutical compositions comprising a such compositions, kits comprising such compositions and methods of use therefor.