The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2025
Filed:
Sep. 12, 2023
Tlc Biopharmaceuticals, Inc., South San Francisco, CA (US);
Taiwan Liposome Co., Ltd., Taipei, TW;
Keelung Hong, San Francisco, CA (US);
Hao-Wen Kao, Taipei, TW;
Yi-Yu Lin, Taipei, TW;
Luke S. S. Guo, San Francisco, CA (US);
TLC BIOPHARMACEUTICALS, INC., Taipei, TW;
TAIWAN LIPSOME CO., LTD., South San Francisco, CA (US);
Abstract
Provided is an anesthetic composition for locally administrating an amide-type anesthetic into a subject in need thereof. The anesthetic composition has multilamellar vesicles with entrapped amide-type anesthetic prepared by hydrating a highly entrapped lipid structure comprising an amide-type anesthetic and a lipid mixture with an aqueous buffer solution at a pH higher than 5.5. Also provided is a method to prepare an anesthetic composition using a simpler and more feasible process for large-scale manufacture and for providing a high molar ratio of amide-type anesthetic to phospholipid content as compared to the prior art. This anesthetic composition has a prolonged duration of efficacy adapted to drug delivery.