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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12280038 B1

PDFFull Text
Date of Patent:
Apr. 21, 2025

Filed:

Jun. 23, 2022

L-pag derivatives for treatment of sleep disordered breathing (sdb)

Applicants:

The University of Chicago, Chicago, IL (US);

Iit Research Institute, Chicago, IL (US);

Inventors:

Michael J. Kates, Philadelphia, PA (US);

Nanduri R. Prabhakar, Chicago, IL (US);

David L. McCormick, Chicago, IL (US);

Miguel Muzzio, Chicago, IL (US);

Assignees:

The University of Chicago, Chicago, IL (US);

IIT Research Institute, Chicago, IL (US);

Attorney:

Norton Rose Fulbright US LLP

Primary Examiner:

Rei Tsang Shiao

Int. Cl.
CPC ...
A61K 31/4164 (2005.12); A61K 31/197 (2005.12); A61K 31/198 (2005.12); A61K 31/216 (2005.12); A61K 31/221 (2005.12); A61K 31/275 (2005.12); A61K 31/381 (2005.12); A61K 45/06 (2005.12); A61P 11/00 (2005.12); C07C 229/30 (2005.12); C07C 255/07 (2005.12); C07D 277/30 (2005.12); C07D 333/24 (2005.12);
U.S. Cl.
CPC ...
A61K 31/4164 (2012.12); A61K 31/197 (2012.12); A61K 31/198 (2012.12); A61K 31/216 (2012.12); A61K 31/221 (2012.12); A61K 31/275 (2012.12); A61K 31/381 (2012.12); A61K 45/06 (2012.12); A61P 11/00 (2017.12); C07C 229/30 (2012.12); C07C 255/07 (2012.12); C07D 277/30 (2012.12); C07D 333/24 (2012.12);
Abstract

Described herein are novel γ- and δ-propargyl carboxylic acids and esters. The novel compositions are antagonists of CSE and may be used to modulate of the activity of the carotid body, therefore providing therapeutic benefits for sleep-related breathing disorders and related conditions.

Find Patent Forward Citations

Kates, Michael. (2025). L-pag derivatives for treatment of sleep disordered breathing (sdb) (U.S. Patent No. 12280038). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12280038

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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