The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2025

Filed:

Feb. 15, 2022
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Edward B. Leof, Rochester, MN (US);

Ruth Lupu, Rochester, MN (US);

Jeong-Han Kang, Rochester, MN (US);

Mi-Yeon Jung, Rochester, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/277 (2005.12); A61K 31/341 (2005.12); A61K 31/365 (2005.12); A61K 31/713 (2005.12); A61P 11/00 (2005.12); A61P 43/00 (2005.12); C12N 15/113 (2009.12);
U.S. Cl.
CPC ...
A61K 31/365 (2012.12); A61K 31/341 (2012.12); A61K 31/713 (2012.12); A61P 11/00 (2017.12); A61P 43/00 (2017.12); C12N 15/1137 (2012.12); C12N 2310/14 (2012.12); C12N 2310/531 (2012.12);
Abstract

This document relates to materials and methods for treating fibrosis (e.g., pulmonary fibrosis). For example, this document provides methods for using one or more fatty acid synthase (FASN) inhibitors to treat a mammal having fibrosis (e.g., pulmonary fibrosis), and/or a complication associated with fibrosis (e.g., hypoxia caused by pulmonary fibrosis).


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