The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2025

Filed:

Jul. 18, 2019
Applicants:

Aicuris Gmbh & Co. KG, Wuppertal, DE;

Friedrich-alexander-universitat Erlangen-nurnberg, Erlangen, DE;

Inventors:

Manfred Marschall, Nuremberg, DE;

Yves Muller, Erlangen, DE;

Heinrich Sticht, Furth, DE;

Jutta Eichler, Erlangen, DE;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2005.12); C07K 14/04 (2005.12); C07K 14/05 (2005.12);
U.S. Cl.
CPC ...
G01N 33/6803 (2012.12); C07K 14/04 (2012.12); C07K 14/05 (2012.12); G01N 2333/04 (2012.12); G01N 2333/05 (2012.12);
Abstract

The present invention generally provides for a novel NEC-targeted strategy for the development of antiherpesviral drugs as well as for a novel antiviral strategy targeting the viral-cellular nuclear egress complex (NEC) for a small molecule-based therapy or prophylaxis to control infections with human cytomegalovirus or other pathogenic viruses of the group of the Herpesviridae. Methods for screening agents/compounds/small molecules modulating/inhibiting the nuclear egress complex of Herpesviridae are provided as well. Specifically novel drug targets of the viral nuclear egress complex of viruses of the Herpesviridae are provided.


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