The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2025

Filed:

Dec. 12, 2019
Applicants:

Dai Nippon Printing Co., Ltd., Tokyo, JP;

National Center for Child Health and Development, Tokyo, JP;

Inventors:

Takuya Okazaki, Tokyo, JP;

Akihiro Umezawa, Tokyo, JP;

Hidenori Akutsu, Tokyo, JP;

Hajime Uchida, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2009.12); G01N 33/50 (2005.12);
U.S. Cl.
CPC ...
C12N 5/0697 (2012.12); C12N 5/0679 (2012.12); G01N 33/5082 (2012.12); C12N 2506/02 (2012.12); C12N 2506/45 (2012.12); C12N 2513/00 (2012.12);
Abstract

A gut organoid includes a tissue structure that encloses a cavity. A method of using the gut organoid includes providing a test drug to the gut organoid in the presence of a buffer solution so that liquid comprising the test drug enters into the cavity, and collecting and analyzing the liquid in the cavity. A method for producing the gut organoid includes plating cells on a cell culture substrate including a surface on which a cell-adhesive region and a non-cell-adhesive region surrounding the cell-adhesive region are formed, and culturing the cells plated on the cell culture substrate so as to induce differentiation of the cells.


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