The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Apr. 17, 2019
Applicant:
The Regents of the University of California, Oakland, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2005.12); C12Q 1/6876 (2017.12);
U.S. Cl.
CPC ...
C12N 15/1065 (2012.12); C12Q 1/6876 (2012.12); C12Q 2600/158 (2012.12);
Abstract
The invention provides scalable methods for measuring chromatin accessibility and RNA expression in the same single cells by connecting chromatin accessibility and transcriptome. Specifically, the disclosure provides a methods for concurrent characterization of gene expression levels and epigenetic landscape within a single cell comprising determining chromatin accessibility and RNA expression in the cell with a splint oligonucleotide.