The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Jun. 25, 2019
Applicant:
Altius Institute for Biomedical Sciences, Seattle, WA (US);
Inventors:
Fyodor Urnov, Seattle, WA (US);
John A. Stamatoyannopoulos, Seattle, WA (US);
Assignee:
Altius Institute for Biomedical Sciences, Seattle, WA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/60 (2005.12); C07K 14/195 (2005.12); C12N 15/10 (2005.12); C12N 15/63 (2005.12);
U.S. Cl.
CPC ...
C12N 15/102 (2012.12); C07K 14/195 (2012.12); C12N 15/63 (2012.12); C07K 2319/50 (2012.12);
Abstract
Provided herein are DNA binding domains comprising a plurality of repeat units, wherein each repeat unit is expanded or contracted in length. Also provided herein are DNA binding domains comprising a plurality of repeat units, wherein each repeat unit is separated from a neighboring repeat unit by a linker. In certain aspects, the linker includes a recognition site. Also disclosed are DNA binding proteins that include a fragment of N-cap sequence of a TALE protein. The TALE protein may be aTALE protein.