The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Apr. 17, 2023
Applicants:
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Adimab, Llc, Lebanon, NH (US);
Inventors:
Zhu Chen, Warren, NJ (US);
Kenneth Ellsworth, Cranbury, NJ (US);
James Milligan, Sevierville, TN (US);
Elizabeth Oldham, Santa Clara, CA (US);
Dietmar Seiffert, Lawrence Township, NJ (US);
Bianka Prinz, Lebanon, NH (US);
Vaishnavi Ganti, Foster City, CA (US);
Mohammad Tabrizifard, Moranga, CA (US);
Assignees:
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Adimab, LLC, Lebanon, NH (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2005.12); A61K 39/395 (2005.12); A61K 39/00 (2005.12);
U.S. Cl.
CPC ...
C07K 16/36 (2012.12); A61K 39/3955 (2012.12); A61K 2039/505 (2012.12); A61K 2039/58 (2012.12); C07K 2317/75 (2012.12); C07K 2317/76 (2012.12); C07K 2317/90 (2012.12); C07K 2317/92 (2012.12);
Abstract
Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.