The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Jun. 23, 2019
Genmab Holding B.v., Utrecht, NL;
Simone Oostindie, Utrecht, NL;
Frank Beurskens, Utrecht, NL;
Ronald Taylor, Keswick, VA (US);
Margaret Lindorfer, Keswick, VA (US);
Hilma Van Der Horst, Utrecht, NL;
Martine E. D. Chamuleau, Amsterdam, NL;
Tuna Mutis, Amsterdam, NL;
Paul Parren, Odijk, NL;
Esther Breij, Utrecht, NL;
GENMAB HOLDING B.V., Utrecht, NL;
Abstract
The present invention relates to anti-CD37antibodies having an Fc-Fc interaction enhancing substitution in the Fc-region of a human IgG, for use as a medicament in combination with anti-CD20 antibodies having an Fc-Fc interaction enhancing substitution in the Fc-region of a human IgG. The invention also relates to a novel composition of anti-CD37 antibodies having an Fc-Fc 5 interaction enhancing substitution and anti-CD20 antibodies having an Fc-Fc interaction enhancing substitution. In particular, the invention relates to compositions wherein the anti-CD37 antibody binds human CD37 and the anti-CD20 antibody binds human CD20. The invention also relates to compositions where the composition is a pharmaceutical composition and the use of such compositions in treatment of cancer and other diseases.