The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2025
Filed:
Aug. 06, 2019
Dragonfly Therapeutics, Inc., Waltham, MA (US);
Gregory P. Chang, Medford, MA (US);
Ann F. Cheung, Lincoln, MA (US);
Daniel Fallon, Winchester, MA (US);
Asya Grinberg, Lexington, MA (US);
William Haney, Wayland, MA (US);
Steven O'Neil, Wayland, MA (US);
Nicolai Wagtmann, Concord, MA (US);
Ronnie Wei, Weston, MA (US);
Bradley M. Lunde, Lebanon, NH (US);
Bianka Prinz, Lebanon, NH (US);
Dragonfly Therapeutics, Inc., Waltham, MA (US);
Abstract
Multi-specific binding proteins that bind to and kill human cancer cells expressing epidermal growth factor receptor 2 (HER2 or ErbB2), but does not kill non-cancerous healthy human cells expressing HER2 are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of HER2 expressing cancer. The invention also relates to multi-specific binding proteins that trigger CD8+ T cell killing of tumor cells.